Let U⊆RnU\subseteq\mathbb R^n be and f:U→Rf:U\to\mathbb R be of . Then for every a∈Ua\in U and all indices i,ji,j,

∂2f∂xi∂xj(a)=∂2f∂xj∂xi(a).\frac{\partial^2 f}{\partial x_i\partial x_j}(a)=\frac{\partial^2 f}{\partial x_j\partial x_i}(a).
Remarks

Apply at each a∈Ua\in U. The C2C^2 hypothesis guarantees that the mixed exist and are near aa.